DPCstruct | MC25175

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)312 ± 32 aa
Standard deviation of domain lengths31.87
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score75.71
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)19.45
Pfam Score91.67
Assigned Pfam label(s) CL0123- PF00140- PF03979

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E0WWH4 2-255 YLMQMGEIPMLDRKSEVTAAKRIERTRLSFRRTMLCNDFMLHAAIDLLQKVADGNLRLDRTIEISVTNTAEKKRVLKRIGPNVATAR…
A0A6B0WF43 14-317 EIQQLIIVGKERGYLLFDEINELLPAGMSSSEELDELFSSLGNAGIEVVESEDKYKEKKRLERAAEGSDEPEFDLTPSPIDKTSDPV…
A0A0F3MJ57 18-340 None
A0A349D122 187-467 None
A0A525PKE6 2-309 None
A0A661NR00 398-663 None
A0A1V4QFU4 2-326 None
Q4ECZ1 12-350 None
A0A6P5UL51 17-393 None
A0A377AD27 1-317 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.