DPCstruct | MC25173

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)411 ± 110 aa
Standard deviation of domain lengths109.84
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score81.81
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)23.64
Pfam Score100.00
Assigned Pfam label(s) CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A069CWK8 142-522 IEVKVPLLTIKNNQFSSEITVREENQYQRWTTRGELNRSSHTIKAELYSQKKQKVYLPYLKKHFEAEVMFDSLSYSLTKTNIGSGQI…
A0A4V2VU36 3-472 QRITVPQAVMNSGKFSSSVFLNDEEAEWLLEGKVQAEDQRMRVEVSSKEPDVELPFLYGKYGLAVSFDKLIFDLKDVKKINKKLLEI…
R5UKE2 3-424 None
A0A3D4W997 37-553 None
A0A832PVU1 325-831 None
A0A7C4E6J3 304-639 None
T2JY31 29-324 None
A0A5C6U6C9 74-313 None
A0A7K1UD94 79-537 None
A0A3C1KWU0 495-889 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.