DPCstruct | MC25156

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)180 ± 21 aa
Standard deviation of domain lengths20.53
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score86.86
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)33.14
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2THD4 14-178 IMLIIELGLVIVTMSLLCCAYPERFRRTLWEIGGENGWNSNPRLRIYFYANYQQPPEIPLIWAQRLSESNLAISVLATAICSTRIIL…
A0A3M7HXH6 108-276 RIPKAMIALLALELPLTVATLTLYGVADPNTYRTKLWQNGYDQGFNSAPNSILYDYANYRTPHVPMVWSAYLVQFNIVISVFSTFIL…
A0A6A6PME4 22-221 None
A0A0U5G6X1 3-193 None
A0A2N6NF80 23-197 None
A0A093Y4C5 767-958 None
X0AX60 32-205 None
A0A1J9RA95 19-215 None
L7J2S9 31-202 None
A0A4S8RCE6 1-134 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.