DPCstruct | MC25117

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)54 ± 3 aa
Standard deviation of domain lengths2.95
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score80.49
Mean fraction of residues predicted as intrinsically disordered0.87
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)62.79
Pfam Score100.00
Assigned Pfam label(s) PF15320

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4TJF0 65-113 TETLQKYEELFAHRFSSEDQEYQQYLNRPADPPPIVEDWRGNQRGRDNR
H2LE75 1-55 MSEATETLKGYEELFVNRFTSEDQEYQEYLNRPADPPPIVEDWRGRAGGNQRELG
A0A6A5FBK9 25-76 None
H9GKA3 39-94 None
A0A7J7FGZ8 296-350 None
A0A091VH07 1-57 None
A0A4Z2G8N8 1-51 None
A0A7J5X776 40-89 None
A0A672G668 1-59 None
G5C9I7 1-57 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.