DPCstruct | MC25096

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)149 ± 19 aa
Standard deviation of domain lengths19.15
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.89
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)25.46
Pfam Score92.95
Assigned Pfam label(s) CL0680- CL0220

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A482RYL0 93-232 AAGLITCAVRRYGHIKLLQKRCREVFTRHFDKQTLNYYYYNPVYGTTSWRKPYCLRNEELFPFMSPYYAACKMQNLYHLFRAREKSR…
A0A418E9Q2 94-232 TGKRIQRMFRCGMARRQMRGMISRVYVKIWDDTRAQFYFYNTSTKTVSWAKPKWVDEDDLMSPRTHQAFLLQEKVDAIRNGPPDAAV…
A0A418ATR1 12-148 None
A0A7S2S4U7 3-149 None
A0A7S4E5F1 131-285 None
W4GY67 224-325 None
A0A7S1GFH7 2-133 None
A0A662X6H6 162-339 None
A0A418B0T5 37-187 None
A0A0L7L8K4 80-229 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.