DPCstruct | MC25090

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)89 ± 9 aa
Standard deviation of domain lengths9.47
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score83.44
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)40.77
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S6B3G2 1-108 MEAKISKKRGTNTKKRNLLPLKNSREFSLQCAKKRLSGSRFRTLNERLYTSHSRDNYSYYQRNPTLFKIYHEGYREQVEKWPIDPLN…
A0A7J7X1Q5 225-307 PPAPSQDNHEARAGALRARMAQRLDGARFRYLNEQLYSGPSSAAQRLFQEDPEAFLLYHRGFQSQVKKWPLQPVDRIARDLRQ
A0A834AAY3 225-307 None
A0A287U6S8 5-77 None
A0A1E1W912 196-295 None
A0A195CPS8 312-402 None
I3S442 1-99 None
Q4UCC8 15-90 None
A0A2R2MQD2 1009-1088 None
A0A2S2PJR5 92-179 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.