DPCstruct | MC25072

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)178 ± 28 aa
Standard deviation of domain lengths27.91
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score76.39
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)47.08
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I9Z6Z3 1-203 MGMEMDPLLHALSYFRRRKFQLCSDLCSQVLEKEPGDQAAWCLKMRALTEMVYVDEIEVDQEGIAEMMLDENAIAQVARPGTSLKMP…
A0A6G0UPQ1 41-226 AAWSLKLACFTEDVYVDELENDEAGLADTYMDDNAIATAARPGTSFSRPITSGKGPSPAVRPRSSTGRPLSGMARPETRLKTGSMEQ…
A0A2R7WB29 18-146 None
A0A183QK68 1-181 None
D8LTW9 3-173 None
A0A1I8I8X7 20-208 None
A0A812RMB3 553-740 None
A0A669PG18 143-354 None
A0A812MX71 663-883 None
A0A0M3KHM2 3-129 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.