DPCstruct | MC25061

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)105 ± 7 aa
Standard deviation of domain lengths7.35
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score77.35
Mean fraction of residues predicted as intrinsically disordered0.56
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)67.37
Pfam Score100.00
Assigned Pfam label(s) PF10491

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A146MBN9 136-241 VVKNLRSMIMDELESALAQQAPPPVQEDPSLYELPPLIIDGIPTPVEKMTQAQLRAFIPLMLKYSTGRGKPGWGRESTRPPWWPKEL…
A0A6J1VY05 1-107 MLRYVRKYKSMILEDLESALLEHAPAPQEVNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDI…
A0A2R7WBB0 5-110 None
A0A4Y7LTJ9 2-110 None
A0A674DAC0 150-253 None
A0A6A4VBA3 140-245 None
A0A1D2N4E5 135-240 None
S4R9R6 1-115 None
A0A8B6D8U1 3-80 None
A0A5N4DYW9 143-247 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.