DPCstruct | MC25009

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)153 ± 11 aa
Standard deviation of domain lengths11.35
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score84.50
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)37.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A2TN51 1-155 MNNVLMIPIHLDALYLKSDRLVVEAMADFSRLPHQDQRDVNPNIANISEEIVSQPFQNQNLYLKAGIHLHWALPDALTKGIQTQDNN…
I4I4C1 2-147 VNSILMIPIHLDALYLKRERLVVEAMADLSIIPYFNRKRDVNPNIAHISEEIVSQPFQNQNLYLKAGIHLHWALPDALTKGIQDSDK…
A0A1V8M7T0 2-154 None
S9QDL1 1-142 None
A0A2R7SI27 6-172 None
A0A845WPP1 8-167 None
A0A846CW71 8-165 None
A0A1C6RV26 3-162 None
A0A3R6RFA8 1-151 None
A0A552L848 1-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.