DPCstruct | MC25008

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)146 ± 12 aa
Standard deviation of domain lengths12.43
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score91.51
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)25.47
Pfam Score100.00
Assigned Pfam label(s) PF09522

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
O25246 1-154 MIDYAKQLGLISLENLENTLKYLKKQKQFIEDNFMITRERFRSHQFGGMDFELSRISYPLLIHSFDDNELSEIVIREQQYGSKTQAM…
D9Q019 27-168 CLDKALNNDTNLKMEIKRVVEEYRNVDTFDKKFTIQRIEDNRYYNEFKLINELTPILRLDGLTDNYYIDIILKPKQRAVGYQAMVFL…
A0A1M6W0D5 48-205 None
A0A7J4KKD1 42-206 None
A0A497RJ69 1-128 None
A0A2H9QQL3 133-285 None
A0A5M0Z9H2 2-134 None
A0A692SR37 95-224 None
A0A7V4IIZ7 132-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.