DPCstruct | MC25002

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)663 ± 53 aa
Standard deviation of domain lengths53.22
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score79.68
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)36.87
Pfam Score93.75
Assigned Pfam label(s) CL0673- CL0392- PF19432

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7E4RVE3 1-566 MLTQKIAAHIADFTPRLWSNNKAQYQYIVIPVVKYPQLLNELFCNIFYLRHLCDTTRFPDWPINDPVSVLRDVLEAWTGEVEKKPPV…
A0A077ZJH8 14-653 WTTGNLMARELLQRIMPEGLLLYLNSTDRAPPLDNDLSLTRCNSDVNDKNYDKLSDQKENLVVDRLIHVRKAVENQLDFLFQHWFHR…
A1Z7S0 637-1335 None
A0A368FDJ1 102-782 None
A0A182EI93 348-936 None
A0A6A5HJ95 1-679 None
A0A3P7DLK6 633-1319 None
A0A1B0DCK4 475-1153 None
A0A397B5F9 1-762 None
A0A3P7SF78 107-749 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.