DPCstruct | MC24996

Metacluster Properties and Pfam Annotations

Number of structural domains69
Mean domain length (aa)162 ± 33 aa
Standard deviation of domain lengths33.22
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.65
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)25.94
Pfam Score100.00
Assigned Pfam label(s) PF04000

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6G3MIJ2 2-117 DLEEELLEIYKNLDNNLDEALKNLENFLKTDYDQILSSLNPVSRAKFELLLAYIMSSIYSIFLKLEGTDTGTHPVKEELNRIRKGMQ…
A0A077ZD54 1-160 MDENSRIDKYVDLHKMVDELQELVQRYTEKPFVDRMTEQSNLQNARTNVELMYVVNALFWCQLRLQNCDAAKHPIMKELNNIKQKLN…
A0A2K5Q5J4 4-130 None
A0A6A4JUZ9 43-179 None
J6F802 79-244 None
A0A7R9A435 12-145 None
A0A4S2N639 8-179 None
A0A834Y177 1-127 None
A0A1J1HA16 19-145 None
U6KUB8 1-198 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.