DPCstruct | MC24985

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)159 ± 15 aa
Standard deviation of domain lengths15.14
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score80.46
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)20.20
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6F9DGU2 63-219 ELTMDDPSEFAMVKHRLLTQPTFLQVTLKKEKKSGNTRYITRGNFVIFLNNTHPFIQQQLREKLDQCEQLLSADKNFALEIDLGPAL…
A0A2C9L0Y8 49-207 RRSYCMERKNEIDDFRHEILQRPLVLQPVLHFGRGFGHYCGLCYSDEPWVILINQTHPKILSRLQMGLDMAKAAIERGQAVEVRFEF…
A0A3M6UUD1 78-230 None
A0A210PR31 62-226 None
A0A6P7TQA2 1-147 None
V4AFF8 2-170 None
A0A7I8V6B9 67-227 None
T1EZQ2 1-175 None
H2ZQ01 54-180 None
A0A3Q3MB92 88-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.