DPCstruct | MC2497

Metacluster Properties and Pfam Annotations

Number of structural domains122
Mean domain length (aa)208 ± 50 aa
Standard deviation of domain lengths49.97
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score76.85
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)27.55
Pfam Score100.00
Assigned Pfam label(s) PF11926

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A3C4T4 24-210 SELYSFDADKIKEKLRIGQMWALYGDEDVEWSDPDMPTCCGKFDVRNSSQAYTSTDSFSHLLKAEPTGSKGEYTIVPRRGEIWALYR…
A0A444YU13 18-189 KMSVSWLNSRSNKELGPMDWIGSGFYKTCGDFTIGKREITGSLNSFSHKVRWAKGNRGIVRIFPRKGDIWALYRNWSPDWNKDTPDE…
A0A6A6LAZ4 326-501 None
A0A803Q587 94-385 None
A0A7N0TX18 474-717 None
A0A2U1QHH6 370-617 None
A0A2G2WX80 122-327 None
A0A1E5UJJ2 191-388 None
A0A7I4BI60 451-619 None
A0A6S7I0G8 529-704 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.