DPCstruct | MC24968

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)146 ± 25 aa
Standard deviation of domain lengths25.43
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.94
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)39.44
Pfam Score100.00
Assigned Pfam label(s) PF12638

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0QSR2 14-149 REGVTKREPIMPRRYTLTHSDITAELFLTIGSTYAFDQINPMRDEVLGEWILNGENYIYMAYVYVDGGGPYNPATATIRNQVFRREL…
K0AYV0 3-126 RYYTLTHSDITGELFLTIDYYYAYDKITSMRDEVFGQWTKVNDRYFLNIYLCIDGEGNIETIPIRDMIFRRELPLALEAIRYGDKEF…
A0A7J0FR96 1-110 None
A0A5N6NZB2 31-126 None
A0A2H5NTA8 11-174 None
A0A822XSP5 55-190 None
A0A4S4EVU5 214-338 None
A0A6S7NS82 1-102 None
T1LCZ8 568-729 None
T0CW04 7-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.