DPCstruct | MC24954

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)81 ± 12 aa
Standard deviation of domain lengths12.21
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score89.75
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)33.80
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R4LKF7 187-268 IPHFSEVTPRKLGQIERAEAALRGLGFHDLRVRHHDEVARLELTPADMVRAVTDPVRREVHAAITAAGFRFVALDLAGVQSG
A0A174BAD8 10-90 YGSVITREKLKKIEIAEEFLLSNNFKQFRVRYYDDLAKIEVLKEDIPKVLQLSEVIIAKFKEIGFNYITLDLEGYRTGSMN
A0A7J2S7B4 251-333 None
A0A1C5N2M2 646-727 None
A0A7C2WLE9 335-415 None
A0A239QSA7 539-615 None
A0A7X9PYX3 177-259 None
A0A843DN51 48-146 None
A0A1M6M1R0 321-408 None
A0A382X503 6-107 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.