DPCstruct | MC24950

Metacluster Properties and Pfam Annotations

Number of structural domains566
Mean domain length (aa)223 ± 45 aa
Standard deviation of domain lengths44.59
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.72
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)19.76
Pfam Score70.27
Assigned Pfam label(s) CL0137- PF20481- CL0704- PF00689- PF00122

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G3IEX9 141-369 None
A0A5E4A6W3 6-179 None
A0A5E4ALM1 82-345 None
A0A7S1N619 1-178 None
A0A1F7M0S1 161-392 None
A0A5D3E7K9 244-467 None
G3I0M9 14-239 None
W0SCI5 455-710 None
R7W3D9 28-250 None
A0A4P9WPA6 153-365 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.