DPCstruct | MC24950

Metacluster Properties and Pfam Annotations

Number of structural domains566
Mean domain length (aa)223 ± 45 aa
Standard deviation of domain lengths44.59
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.72
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)19.76
Pfam Score70.27
Assigned Pfam label(s) CL0137- PF20481- CL0704- PF00689- PF00122

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C0B7J8 26-240 None
A0A5C8X5N2 33-245 None
A0A538RY83 2-174 None
A0A6A6KK84 57-307 None
A0A287P072 22-312 None
A0A287P786 39-299 None
F6HST1 106-356 None
A0A4S5AIJ2 61-297 None
A0A2P5NRB8 7-228 None
D8SFB1 283-508 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.