DPCstruct | MC24950

Metacluster Properties and Pfam Annotations

Number of structural domains566
Mean domain length (aa)223 ± 45 aa
Standard deviation of domain lengths44.59
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.72
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)19.76
Pfam Score70.27
Assigned Pfam label(s) CL0137- PF20481- CL0704- PF00689- PF00122

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J7LQK0 164-367 None
D3BMN9 27-299 None
A0A7J7LVE2 73-282 None
A0A4U5QSX9 16-198 None
A0A4U5R0T5 12-222 None
A0A2T7PQC8 73-334 None
A0A1X2GTG2 201-516 None
A0A1Q2ZU79 519-755 None
A0A5J4WFE9 7-253 None
A0A7J7M9M8 208-386 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.