DPCstruct | MC24950

Metacluster Properties and Pfam Annotations

Number of structural domains566
Mean domain length (aa)223 ± 45 aa
Standard deviation of domain lengths44.59
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.72
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)19.76
Pfam Score70.27
Assigned Pfam label(s) CL0137- PF20481- CL0704- PF00689- PF00122

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R8GZB9 2-119 VPHYAVCIRDGEKMNLKVEELTLGDLIDVKLGDRLPADIRIIDSKNFKVDNSSLTGESEPQSRSREFTHENPLETKNIAFFSTHAVE…
A0A3Q1AN93 42-291 KRRTVFLLKLYKGNKIRTTKYSLLSFLPKNLFEQLHRFANVYFIFLAALNFVPVVEAFQPEISVIPIILVLSVTAVKDIWEDYCRFK…
A0A444X418 61-235 None
A0A819MST1 348-580 None
A0A2D6QTI5 173-423 None
A0A534WFU0 555-757 None
K8EKJ0 439-686 None
A0A0C2IX18 213-482 None
A0A1A7XFN7 2-212 None
A0A2D0Q571 3-293 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.