DPCstruct | MC24945

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)109 ± 3 aa
Standard deviation of domain lengths3.40
Length coefficient of variation0.03
Mean AlphaFold2 pLDDT confidence score83.87
Mean fraction of residues predicted as intrinsically disordered0.72
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)46.59
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3E2NE12 5-112 NPETYLQKALKNQGLEDTPARMKENWIDGDYKYTVRVHEGNSTYTDADSIYRVSRKSTVVDEFGQGRGLEYLGTDGNWYQESVLKEF…
A0A4R2VSS7 1-106 MEGFESGEVIPRGYKKEWIAGGYKYEVRVHPSNKKYAESKDILRVGRKQVDADGKGIGKGMEYLDIHGEWHPEKVLKPKSKNGIPNP…
H1GFL1 28-138 None
D1YPJ3 29-142 None
A0A2T7BMS2 584-687 None
A0A4U2Z0Y3 248-353 None
A0A1H9PX83 130-240 None
A0A7X5CUN8 477-590 None
A0A1I1RYC6 79-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.