DPCstruct | MC24926

Metacluster Properties and Pfam Annotations

Number of structural domains165
Mean domain length (aa)140 ± 32 aa
Standard deviation of domain lengths31.54
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score80.67
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.56
Pfam Score98.81
Assigned Pfam label(s) CL0123- CL0236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A235BXH2 16-163 VYEKSLSSIIKKVEESKHKAITTVNKLLIELYWYIGKTITELQERSKWGDGVVERLSQDLRMKYPNQSGFSSRNLWDCKRFYLAYRN…
A0A3D9AL98 6-144 DSLFQSIKEIINQSREKVFRIANSTLLLTYWQIGQLIVEDEQKGKERAEYGKYTLKKLSKKLTLEFGKGFDESNLRNMRSFYNIFPI…
A0A4S4G3Q4 40-192 None
R7KMS4 24-132 None
A0A7V8BMJ3 6-180 None
A0A1S1Y7N3 3-91 None
A0A5C7Q737 34-198 None
A0A0F9C438 68-246 None
A0A7W0ENW2 14-126 None
A0A6C1C9A2 1-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.