DPCstruct | MC24898

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)96 ± 7 aa
Standard deviation of domain lengths7.08
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score91.86
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)28.65
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H1LV09 12-107 LNFIFCSHPLDKKKVDEDYFEEYQAAGLNHACALFSYEDLERGKMSLSGEDIKGITIYRGWMMSPHMYENFYNMLLERGIQLINSPK…
A0A6J4E8M8 4-101 MHLLYPSSPDNPNIPDETFAEEFAAAKAAGLGCSLFSCEELELQRFKPKPALEEGARVLYRGWMLAPDAYGYLHASIVSRGAIPVTS…
A0A4R4UH71 1-100 None
A0A1G5ILH9 92-187 None
C2JWK4 4-105 None
A0A1Q9F6F6 35-124 None
A0A543AYI3 25-123 None
A0A011V5D2 1-107 None
A0A6B2U3F2 1-100 None
A0A0H3IA36 1-77 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.