DPCstruct | MC24892

Metacluster Properties and Pfam Annotations

Number of structural domains186
Mean domain length (aa)104 ± 20 aa
Standard deviation of domain lengths19.64
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.05
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)24.25
Pfam Score98.86
Assigned Pfam label(s) CL0104- PF01329- CL0662

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J9Y846 6-94 None
A0A4S8MYP0 17-201 None
A0A0K0E506 124-219 None
A0A7R7WZF0 13-110 None
A0A4S4D3Z0 33-131 None
L8HG82 8-105 None
A0A091E2M6 212-319 None
A0A1E3IC88 464-614 None
A0A453PZ05 1-78 None
A0A654M3L2 315-418 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.