DPCstruct | MC24892

Metacluster Properties and Pfam Annotations

Number of structural domains186
Mean domain length (aa)104 ± 20 aa
Standard deviation of domain lengths19.64
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.05
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)24.25
Pfam Score98.86
Assigned Pfam label(s) CL0104- PF01329- CL0662

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0BRA7 32-132 None
A0A5D6XFX1 86-195 None
A0A1Y3E3D6 17-132 None
A0A402ANX7 117-235 None
H5XIA3 130-231 None
A0A2Z7CVC6 14-104 None
A0A3P6BQJ4 1-85 None
A0A4R2DPK5 369-475 None
A0A094ANE9 1-94 None
A0A2G8SPH1 3-102 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.