DPCstruct | MC24892

Metacluster Properties and Pfam Annotations

Number of structural domains186
Mean domain length (aa)104 ± 20 aa
Standard deviation of domain lengths19.64
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.05
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)24.25
Pfam Score98.86
Assigned Pfam label(s) CL0104- PF01329- CL0662

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C5ZQG7 3-82 ELISKGWKIEEGKLSKTFEFNNFKEVVMFFNAVAWEAEKMNHHPDTFITYKKCHINLFTHSEGKITNKDVELARKIENIF
A0A259DT37 13-110 QPITPNSQRMVIPTVESYLSVLPGWQAGFDYNSIERSIQFKNHYQVMAFLNALAFISHEQDHHPEICYGYNKVTIKLTTHTIKGVSL…
A0A2R6CQE2 2-97 None
A0A4V5ND60 6-111 None
A0A353RWF6 183-279 None
A0A834Y1W6 350-447 None
A0A438NFM3 44-149 None
K2SRT0 170-270 None
A0A199VS52 1-85 None
A0A2D6E4G3 16-118 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.