DPCstruct | MC24885

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)181 ± 48 aa
Standard deviation of domain lengths48.48
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score73.94
Mean fraction of residues predicted as intrinsically disordered0.57
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)22.43
Pfam Score100.00
Assigned Pfam label(s) PF10180

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4G6T4 8-184 KKQRGKLKADKSKKEVAKTHVKFDDNGDKVVPKKRARVAKKKDADEVKEGGGKSDRSPEMIQQAKYYLEQWQKRDEPKADDELPWKF…
A0A0G4IIL3 21-150 VERQKKRKQELKAARVVKGIAKQEALDKERAAKSLDDALQYLTLWDTNRSEWKFHKKRQITLLKNMLDRTRVPKPQFKILLRYLGGL…
A0A369S3V4 17-150 None
M3D9K1 136-362 None
A0A834QU34 112-296 None
A0A1Y1V7S2 128-274 None
E7FH60 77-257 None
W6Z650 275-444 None
A0A1A6A2N1 48-311 None
A0A317SGT6 261-400 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.