DPCstruct | MC24878

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)138 ± 11 aa
Standard deviation of domain lengths10.70
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score88.23
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)32.51
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0W8ELU6 33-178 VLGDVSYVRKFGTEPTPTTDEHLRVTAHFQYVEAVLQRKGTRALTNRQRRNRYHALKLLRNYWMAGQYPANYDFPHERRPCLIDRTG…
A0A1S9AUZ4 28-165 VSYKPAAVEPVLSVADEHARIAAHLQYTEDVLRHKGTRGMPSHLRRRRYRTLKLLHAYWTTGLFPIDTEHPARRRPCLMDRDGRVCA…
A0A848L8R2 35-181 None
A0A815QCQ8 34-173 None
A0A4R6K5Z1 6-135 None
A1ZXF9 28-170 None
A0A356KX86 28-145 None
A0A1M3IEJ3 42-176 None
A0A2R6LXG3 11-137 None
A0A815PIG5 11-160 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.