DPCstruct | MC24862

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)89 ± 7 aa
Standard deviation of domain lengths7.00
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score89.52
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.58
Pfam Score100.00
Assigned Pfam label(s) CL0028

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q4TK98 225-312 VARTMLIMPNYQTDSINTIVTMSAPHARPPVTFDPQIVQIYEDINRHWRDSYSQRWADDNPLRQVTLVSIAGGGLDTVVPSDYASLES
A0A0R3WPV9 150-233 MGGVVAHYALAKAKFDPSMVNWVITLASPLRSPVVALGVHLLRIYERIYKFWRSVPLDNSYEHVTFLSITGGISDHQVWDGLGK
A0A7J6JHE0 358-445 None
A0A317SF20 22-105 None
A0A0R3T3K1 593-672 None
A0A7R9PB19 256-346 None
A0A453KIL2 11-100 None
A0A226MP59 181-270 None
A0A2P2K408 5-108 None
A0A5C7HF18 221-321 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.