DPCstruct | MC24856

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)461 ± 88 aa
Standard deviation of domain lengths88.31
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.22
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.31
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)22.42
Pfam Score95.48
Assigned Pfam label(s) PF18077- CL0188

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G2W8R3 2-301 IAMEKLLEEKEKGLETKVAENDTICAENTELRKRVEEQGINARDAERMKREIQALERDIGDIENQRNEWEEKAWDLDSTARNEYRKL…
A0A314UG32 21-505 LSSINSYLASHSMQIFLKFPIPSAKEITETLKFLVARLDYPNPKLEDDLPVILKFLKCPFKPNKSMLRNPTVNHHQWPTLLAVIHWL…
A0A822XZ04 3-295 None
A0A1R2D338 1-353 None
A0A4Y7JCQ0 52-539 None
A0A6A6L0I7 406-818 None
A0A3N4KM57 26-562 None
A0A1A8BI74 10-358 None
A0A0G4KWR5 2-515 None
A0A1R3I3H8 590-1066 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.