DPCstruct | MC24836

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)421 ± 62 aa
Standard deviation of domain lengths62.03
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score74.51
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.20
Pfam Score69.09
Assigned Pfam label(s) PF11992- CL0125

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R5D8S2 7-477 TEPQGTERQESGRPVGVLATTAAALLGGAGAAWVIGGVFGGGLARLTAIGGAVLGALIAWASYRTSRPALMQLLAVPAALVAGSLLV…
A0A2V9NIF5 13-448 AAAIRRYFDVVLYLLIFTGFGTLASTGSLDFPTVLIVSGALLFRGYILARRLQVILSERWTNLLTIACFALFVADEFVISRTFLASA…
A0A7T9EBV4 1-419 None
K2G4E4 215-640 None
A0A6B0Q4B2 10-401 None
E7NRY6 9-451 None
A0A554WA05 18-353 None
A0A5C1QCV1 9-465 None
A0A5C8M369 1-331 None
A0A373Q354 23-474 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.