DPCstruct | MC24833

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)289 ± 37 aa
Standard deviation of domain lengths36.97
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.79
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)23.58
Pfam Score83.33
Assigned Pfam label(s) CL0291- CL0237

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V9JAS3 98-401 MRTESELRQVAADDLRVAFGLLDARHVAGDASLTMSSRTQLMADWRQGAKKRLPGMAKMTRERWARFGDLAHSTTPDLKEAHGGLRD…
A0A2V9NCR9 4-284 VRCAKRRVHNCSARLPEVTRSRHAKYGNTVFHLEPNIKEAPGGLRDYNVACWMALLSAIDQECRWPATESFLPDSTRQLKPALQFLS…
A0A7H4SAY9 2-257 None
A0A2V8UE77 9-265 None
A0A848QFY4 1-279 None
A0A7J5UK56 2-297 None
A0A538CAJ6 7-335 None
A0A7W1UCM5 192-414 None
A0A3N5ZRL6 121-437 None
A0A2V6R644 573-896 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.