DPCstruct | MC24826

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)153 ± 12 aa
Standard deviation of domain lengths12.22
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score92.70
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)46.77
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A498ETH5 8-153 QLHEAYSKYAMSRVSCVFCIMSSEADLMASAGCVDNHEVYVELVELEAESTFGFQGNRWLADVAPHLLPPELRAAIVDAKEKAVLRQ…
A0A1G6PSK7 152-303 ELHEAYTKYLMTRVSCVFCIMSSAGDLIASTTCPDNQDIYRTMVELEATSTFAFQSNNWLGDVAPHLLGSELADRLALAKEAARVRE…
A0A072TPX0 124-285 None
A0A2Z5ACI8 16-164 None
A0A810YDH9 42-222 None
A0A4Q3QC30 1-155 None
A0A1I2I118 20-150 None
A0A069PLN3 3-148 None
A0A4V2RFR1 78-235 None
A0A094X5E3 14-165 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.