DPCstruct | MC24823

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)46 ± 2 aa
Standard deviation of domain lengths2.05
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score92.48
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.95
Mean intra-cluster local Distance Difference Test score0.95
Mean intra-cluster sequence similarity (%)50.71
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X6CU07 3-49 KIVIIGAGITGLSTAYALLERGYDVTVLDRQRYAAMETSFANGGQIS
A0A498EPK7 3-45 QQVIVIGGGVVGLTSAWWLAQAGYRVTLLERAQEVGSGSSYGN
A0A249Q5S4 304-346 None
A0A6G3HN45 3-47 None
A0A4R6YDF5 2-48 None
A0A4P0Y9L4 3-50 None
A0A378EG68 3-50 None
A0A4Q3T228 2-48 None
I3UDI8 9-57 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.