DPCstruct | MC24779

Metacluster Properties and Pfam Annotations

Number of structural domains272
Mean domain length (aa)251 ± 55 aa
Standard deviation of domain lengths55.12
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.04
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)23.93
Pfam Score81.85
Assigned Pfam label(s) CL0023- PF01576- CL0220- CL0680- CL0266

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I7WBL9 539-753 None
J9LWT4 502-736 None
A0A146L935 838-1067 None
A0A0P4W0H8 90-385 None
R1DYV8 688-967 None
A0A7S4MZW5 238-575 None
A7S0W8 444-692 None
A0A178UU18 2-247 None
A0A6F9A0S5 363-633 None
A0A0A9YEQ3 3-247 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.