DPCstruct | MC24779

Metacluster Properties and Pfam Annotations

Number of structural domains272
Mean domain length (aa)251 ± 55 aa
Standard deviation of domain lengths55.12
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.04
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)23.93
Pfam Score81.85
Assigned Pfam label(s) CL0023- PF01576- CL0220- CL0680- CL0266

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K7F551 2-219 None
A0A670JA84 837-1067 None
A0A7J0G5C3 1001-1242 None
A0A067CNE1 584-881 None
E9QEL6 451-750 None
A0A812DYD4 847-1143 None
A0A2K3NUZ5 21-324 None
A0A183GZM1 264-515 None
A0A183HHM7 38-321 None
T1HPG6 15-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.