DPCstruct | MC24779

Metacluster Properties and Pfam Annotations

Number of structural domains272
Mean domain length (aa)251 ± 55 aa
Standard deviation of domain lengths55.12
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.04
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)23.93
Pfam Score81.85
Assigned Pfam label(s) CL0023- PF01576- CL0220- CL0680- CL0266

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C6KSY1 614-941 None
A0A144A488 969-1198 None
A0A0K0DR02 23-318 None
A0A0K0DQ93 10-196 None
A0A822DZE1 51-296 None
A0A2A4JJR9 331-620 None
Q8IHW0 1056-1324 None
A0A336N3K1 252-535 None
A0A834BST7 2-231 None
A0A6P6YAB2 541-760 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.