DPCstruct | MC24779

Metacluster Properties and Pfam Annotations

Number of structural domains272
Mean domain length (aa)251 ± 55 aa
Standard deviation of domain lengths55.12
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.04
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)23.93
Pfam Score81.85
Assigned Pfam label(s) CL0023- PF01576- CL0220- CL0680- CL0266

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6H5HGN7 232-422 None
Q8SS35 528-823 None
L2GK99 421-715 None
A0A4Y2SS71 3-168 None
U4US82 165-408 None
A0A663MVW1 295-609 None
A0A182MND6 537-844 None
A0A4W6CCY2 223-522 None
A0A0M0K1V9 469-724 None
A0A1Y2G1K3 35-287 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.