DPCstruct | MC24750

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)235 ± 15 aa
Standard deviation of domain lengths14.61
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score85.78
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)28.10
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A137Q596 1-262 MREGHLLPILISILISLMTEMYTTKYDPQKNRIAPDLSDGHFIHNKQRGGNTITDFWTCKGEVEVKDSDTLGYFIHYDCELCDSVDF…
A0A4Y7Q3I7 150-363 VREGHLLPITMAVCMAILTEIYTTTSAAGSKEKRLRFHYRSTPISDFGIAVGSADVKNQDKLAYWLPNGEFMKGQDPDEHCWIYFTT…
A0A409W4D2 3-245 None
A0A4Y9ZCZ6 394-607 None
A0A137QXT5 297-541 None
K5WPA2 9-245 None
A0A4Q2DGF5 82-319 None
A0A409X8L9 67-292 None
A0A0C3KQ27 75-297 None
A0A137QQ70 222-467 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.