DPCstruct | MC2475

Metacluster Properties and Pfam Annotations

Number of structural domains94
Mean domain length (aa)184 ± 34 aa
Standard deviation of domain lengths34.45
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.27
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)24.09
Pfam Score57.98
Assigned Pfam label(s) PF00460- PF06429- PF07559

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E6PCM2 3-181 GIQWAAEAMAAAQQRLDIATSNLANASSDAFQRLRARGTIDRSGVRIRAVADTRPGALRPTGRPFDLAVSGGALQLRDARGATVRLT…
A0A257TTB5 96-293 ATKILTEAVTALKTKLAVIGHNMANADTIGFKRSRVMFEDGRYRQVKLPGASDAFNNYAPTGLAIGLGVRVQATQILFDQGPIQVTN…
H6SME5 131-340 None
A0A7X8E524 1-142 None
A0A7V3ABZ5 52-250 None
A0A1H4LLG9 160-315 None
M6VAQ7 25-246 None
A0A7X2PKL4 1-142 None
A0A656GZX5 1-112 None
A0A523FEA3 3-209 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.