DPCstruct | MC24748

Metacluster Properties and Pfam Annotations

Number of structural domains234
Mean domain length (aa)127 ± 25 aa
Standard deviation of domain lengths24.71
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score88.15
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.99
Pfam Score97.94
Assigned Pfam label(s) PF00082- CL0193- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A527IEI4 1-85 None
A0A6G0UEJ9 216-377 None
A0A377THL8 3-121 None
A0A166VK28 40-175 None
A0A318Z5B0 3-129 None
A0A812XJA0 266-405 None
A0A812YM17 271-356 None
A0A4P0TDJ8 124-245 None
D5P646 9-76 None
A0A2V7UHE7 140-241 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.