DPCstruct | MC24748

Metacluster Properties and Pfam Annotations

Number of structural domains234
Mean domain length (aa)127 ± 25 aa
Standard deviation of domain lengths24.71
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score88.15
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.99
Pfam Score97.94
Assigned Pfam label(s) PF00082- CL0193- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A090X4J0 1-94 MAPMTRSRANNEGKVATDELQGLYYEQRASAGLIISEGSQVSEQAVGYINTPGIHTDAQVEGWKKVTKRVHDKGGKIFIQLWHVGRM…
C7IVE6 62-171 MLLKEGKIGKIKLKNRLIMLPTVTNLSNEGFVSEREVEYYKRRSKGVSLVIVGASYVNKLGKFFVNQIGIDDDDKIEGLRKLSEVIH…
A0A4S2MNH3 129-263 None
A0A2N9IDA7 365-512 None
A0A6A6L922 1-106 None
A0A6P8BPT4 109-242 None
A0A5N6EQQ3 173-323 None
A0A068UQF0 2-82 None
A0A0B8PFG3 5-137 None
A0A084RSA1 804-986 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.