DPCstruct | MC24739

Metacluster Properties and Pfam Annotations

Number of structural domains165
Mean domain length (aa)88 ± 18 aa
Standard deviation of domain lengths17.86
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.31
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)29.63
Pfam Score91.13
Assigned Pfam label(s) CL0509- CL0198

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V5ZF24 3-68 VPDVRVEELDFSVRTYNCLKRAGISSVRDLVHRTHHELMSIRNFGKRSLLEVREKLAQLGLTLRGE
Q14PS2 27-109 NEIQEQITIWLEMDETERNQLLNHSIDDLEITQRTQICLEKAKIYRLSDLVSKTENEIKNIKNLGEKSLTEIKEKMHELGLHF
A0A7C1DL71 22-131 None
A0A1F6XIJ6 79-142 None
L0DRP4 127-223 None
A0A0S8BQP2 2-71 None
A0A1B8PU52 19-129 None
A0A7C0Y666 9-120 None
A0A1B0C7F8 408-501 None
A0A5C5NP52 5-70 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.