DPCstruct | MC24737

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)117 ± 24 aa
Standard deviation of domain lengths24.26
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.04
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)14.61
Pfam Score100.00
Assigned Pfam label(s) PF20874- PF11083

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R7TZN0 3-93 KVWHTLVVSYEQVVAEFYNSLIIAMPQNKKYKKYCFYFPKKMASYKNDSWLLRFTDDWNFNVFLKVKNNVGEYETIDEVKLTAQELI…
A0A6I7GNZ2 10-117 KNQNVENYFISKGFIPFTTDKASFINLPNHNRHIGFWLSNKFIYPSEKHSEQVAIGLIYDNSYPIVKYDENLKRHIWKYLTGTELIN…
A0A1I2EHI1 2-85 None
A0A292G1X2 71-161 None
A0A4D8RL32 29-103 None
A0A150NJZ6 36-183 None
A0A6M5FYE6 183-274 None
A0A7Y8VR22 402-509 None
A0A1C6G879 1-126 None
A0A1C6GBE9 479-596 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.