DPCstruct | MC24726

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)182 ± 29 aa
Standard deviation of domain lengths28.65
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.42
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)33.00
Pfam Score100.00
Assigned Pfam label(s) CL0182

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K2PI82 2-150 ILFALGGSTYGMAEETLAFYALIIPVMIAVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGQGMGLRFFMLVVLTGI…
A0A2S1ETY4 17-177 ALSTKTKGKEFILVFLVTVLLALGGTLCGIEEEAVAFYPILAPVFIAMDYDSIVCVGAIFLASSLGTTFSVINPFSVVIASNAAGTT…
U7V0K3 11-190 None
A0A1S8DM02 3-146 None
A0A840MAN3 68-223 None
A0A084U4W6 192-394 None
A0A396Q462 8-192 None
D6S3Z2 128-345 None
A0A7J9VHW8 37-216 None
A0A7X9K9Q1 79-311 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.