DPCstruct | MC24715

Metacluster Properties and Pfam Annotations

Number of structural domains476
Mean domain length (aa)244 ± 39 aa
Standard deviation of domain lengths39.46
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.13
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.96
Pfam Score98.79
Assigned Pfam label(s) CL0052- CL0181- CL0517- CL0472- CL0129

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3A0C9G6 89-325 None
A0A7X6DR84 14-247 None
A0A5B8N1G5 110-305 None
A0A523D2L2 1-352 None
A0A537TIX6 91-344 None
A0A438DP70 175-436 None
A0A3A0BHZ5 46-395 None
A0A4Y7L063 433-640 None
A0A3M8DUY9 9-221 None
A0A182FPR9 21-291 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.