DPCstruct | MC24715

Metacluster Properties and Pfam Annotations

Number of structural domains476
Mean domain length (aa)244 ± 39 aa
Standard deviation of domain lengths39.46
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.13
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.96
Pfam Score98.79
Assigned Pfam label(s) CL0052- CL0181- CL0517- CL0472- CL0129

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I4IXX3 237-511 None
A0A523RCC8 15-314 None
A0A3A9KI84 72-314 None
A0A2Z4R998 3-200 None
A0A2U1LLT5 317-517 None
A0A1Q9NZB0 11-337 None
A0A024TIU5 45-337 None
B8JEG6 328-545 None
A0A6A5N6P4 331-569 None
A0A142Y0V3 28-348 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.