DPCstruct | MC24715

Metacluster Properties and Pfam Annotations

Number of structural domains476
Mean domain length (aa)244 ± 39 aa
Standard deviation of domain lengths39.46
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.13
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.96
Pfam Score98.79
Assigned Pfam label(s) CL0052- CL0181- CL0517- CL0472- CL0129

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R4VRF4 167-384 None
L1J451 1-216 None
A0A847NSY5 2-199 None
A0A812XVX6 13-257 None
A0A1V5PL31 188-480 None
A0A353M056 6-250 None
A0A651H133 114-375 None
A0A2U3CFF0 13-256 None
A0A7S1FTS1 32-336 None
A0A6J4R415 3-236 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.