DPCstruct | MC24715

Metacluster Properties and Pfam Annotations

Number of structural domains476
Mean domain length (aa)244 ± 39 aa
Standard deviation of domain lengths39.46
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.13
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.96
Pfam Score98.79
Assigned Pfam label(s) CL0052- CL0181- CL0517- CL0472- CL0129

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S5AHZ3 207-430 None
A0A2S3QIH5 88-308 None
A0A538BC77 51-271 None
A0A2E7ESX5 4-204 None
A0A5S9IR61 712-938 None
A0A6G1D5Z6 12-209 None
A0A3S5J5H5 11-226 None
A0A536ND32 47-281 None
A0A2W4MMA0 8-245 None
E0VU35 188-450 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.