DPCstruct | MC24709

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)161 ± 19 aa
Standard deviation of domain lengths19.21
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score67.13
Mean fraction of residues predicted as intrinsically disordered0.58
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)46.03
Pfam Score87.51
Assigned Pfam label(s) PF00010- PF12232- PF01586

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0L8HXY3 2-133 ASSPSSSSSSSSASDEVDEHVPHVLAPGYHGPNRRCLLWACKACKKKTVTIDRRKAATLRERRRLRKVNEAFETLKRRTCPNPNQRL…
A0A3Q0FMC9 20-176 GALQQLEMAEGSPLYPGSDGTLSPCQDQMPPEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRL…
G1KPV6 53-222 None
A0A1B0AVC0 82-216 None
A0A803K099 55-175 None
A0A6P7ZUE4 11-199 None
A0A4Y2IQ79 161-336 None
E3MS04 77-258 None
A0A1J1J6V5 71-228 None
A0A7M4E604 23-164 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.